Resorufin benzyl ether is a fluorometric probe that acts as a substrate for cytochrome P450 (CYP)3A4.{27561} It is typically used near its apparent Km value of 30 µM to screen the inhibition/activation potential of test compounds, to predict potential drug-drug interactions, or to monitor other CYP450 activities.{27561} Upon enzyme cleavage, resorufin benzyl ether generates a red fluorescent product (ex. 571 nm/em. 585 nm).
产品描述
A fluorometric probe that acts as a substrate for CYP3A4; typically used near its apparent Km value of 30 µM to screen the inhibition/activation potential of test compounds and to predict potential drug-drug interactions