- 中文名称
组蛋白H3K9Me2单抗(克隆9D8)
- 英文名字
- Histone H3K9Me2 Monoclonal Antibody (Clone 9D8)
- 供应商
- Cayman Chemical
- 产品货号
- 18072-100
- 产品报价
- ¥询价/100ug

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- Histones are nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. The basic structure is a 146 bp strand of DNA wrapped around a histone octamer containing pairs of the four core histones (H2A, H2B, H3, and H4). Histones are subjected to numerous post-translational modifications including methylation. Histone lysine methylation is an important post-translational modification linked to diverse biological pathways including gene transcription, heterochromatin maintenance, and double stranded DNA break repair.{20250} Most lysine methylation events are carried out by a SET domain containing HMTase, and methylation at lysine 9 of histone 3 (H3K9) is important for the recruitment of the heterochromatin protein 1 and the establishment of heterochromatin.{20252,17726,29238} The SET1/MLL (KMT2) family of methyltransferases is the principal enzyme family responsible for H3K9 methylations. {19551,19556} The WDR5/RbBP5/Ash21/DPY-30 subcomplex is required for the H3K9 dimethylation activity of the MLL1 core complex.{20268}
- 应用类型
- ELISA,FC
- 免疫原
- Synthetic peptide from human Histone H3 aa 1-30 (di-methyl K9) conjugated to KLH
- 来源宿主
- 小鼠
- 反应性
- 人
- 保存建议
- 建议您收到Cayman Chemical的组蛋白H3K9Me2单抗(克隆9D8)产品后将其置于-20℃保存.
- 其他
- Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒,其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒,如:类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等;也提供多种高质量试剂,包括:类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

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