Voriconazole-d3 contains three deuterium atoms located on the β methyl group. It is intended for use as an internal standard for the quantification of voriconazole (Item No. 15633) by GC- or LC-mass spectrometry. Voriconazole is a triazole, antifungal agent that inhibits a broad range of pathogenic yeasts, including Candida (MIC = 0.03-8 µg/ml), and filamentous fungi such as Aspergillus, Scedosporium, and Fusarium.{20805,25332} Its inhibitory action results from its ability to inhibit the synthesis of ergosterol, the major sterol of the fungal cell membrane.{25332,24400,25587}
产品描述
An internal standard for the quantification of voriconazole by GC- or LC-MS
