YS-035 is a verapamil derivative that dose-dependently blocks calcium uptake via Na+/Ca2+ exchange in diverse types of cells (Ki = 28 ?M).{28773} It inhibits calcium uptake by muscle cells, brain synaptosomes, and kidney fibroblasts.{28773} YS-035 also prevents calcium release from mitochondria induced by Ruthenium Red but not by uncouplers, respiratory inhibitors, or a chelating agent.{28773} YS-035 is used to characterize the role of calcium currents in smooth muscle and neuronal electrophysiology.{28774,28775}
产品描述
A verapamil derivative that dose-dependently blocks calcium uptake via Na+/Ca2+ exchange in diverse types of cells (Ki = 28 ?M); also prevents calcium release from mitochondria induced by Ruthenium Red but not by uncouplers, respiratory inhibitors, or a chelating agent
