COX-1 and -2, also called prostaglandin endoperoxide H synthases-1 and -2, are key regulatory enzymes in the prostaglandin biosynthetic pathway. COX enzymes catalyze the committed step in the conversion of arachidonic acid (Item No. 90010) to prostaglandin H2 (Item No. 17020). These enzymes are the major targets for NSAIDs that are used to reduce pain, inflammation, and fever.{8931}
产品描述
Peptide sequence: 24-599 (full-length) • Source: Recombinant N-terminal His-tagged protein expressed using the baculovirus system • Mr: ~70 kDa
产品形式
80 mM Tris, pH 8.0, containing 0.1% polysorbate 20, 300 µM DDC, and 10% glycerol
