Tianeptine is an atypical antidepressant with diverse actions, most notably on the glutamatergic system.{28647,28646} It attenuates glutamate release and modulates the function of the AMPA receptor.{28646,28648} Tianeptine also acts as an agonist of the µ-opioid receptor (EC50s = 194 and 641 nM for human and mouse receptors, respectively).{28645} It is as effective as fluoxetine (Item No. 14418) in the management of post-traumatic stress disorder.{28644}
产品描述
An atypical antidepressant with diverse actions, most notably on the glutamatergic system; attenuates glutamate release and modulates the function of AMPAR; acts as an agonist of the µ-opioid receptor (EC50s = 194 and 641 nM for human and mouse receptors, respectively)
