Galantamine is an alkaloid originally isolated from the bulbs and flowers of various Galanthus species. It allosterically potentiates nicotinic acetylcholine receptors, as well as inhibits acetylcholinesterase (IC50 = 636-2010 nM), thereby promoting acetylcholine activity in the brain.{24085,17054,25283} Galantamine has been used in the clinical treatment of vascular dementia and Alzheimer’s disease symptoms and as a nootropic for other cognitive impairments.{23018,17054,25143}
产品描述
An allosteric potentiator of nAChRs and inhibitor of acetylcholinesterase (IC50 = 636-2010 nM); promotes acetylcholine activity in the brain and used in the clinical treatment of vascular dementia, Alzheimer’s disease, and other cognitive impairments
