The C2 domain of conventional PKC isoforms mediates calcium-dependent translocation. Peptides from that region can block PKC translocation and inhibit function, both in cells and cell lysates.{28521} PKCα (C2-4) inhibitor peptide is a synthetic peptide that blocks PKC activity in HepG2 cells stimulated with calcium and pancreastatin when applied at 10 µM.{28522}
产品描述
A synthetic peptide that blocks PKC activity in HepG2 cells stimulated with calcium and diacylglycerol when applied at 10 µM