Protein kinase Cɛ (PKCɛ) is a calcium-independent, phospholipid- and diacylglycerol-dependent serine/threonine kinase involved in diverse signaling pathways, including those involved in neuronal signaling, cytoskeletal function, and inflammation.{9056} PKCɛ inhibitor peptide is a synthetic peptide corresponding to an amino acid sequence found in the amino terminal C2 domain of most mammalian forms of PKCɛ.{28594} It selectively and reversibly inhibits the translocation of PKCɛ to intracellular membranes, blocking activation.{28594} PKCɛ inhibitor peptide is commonly used in cells to evaluate the role of PKCɛ in various cellular responses.{28596,28597,28595}
产品描述
A synthetic peptide corresponding to an amino acid sequence found in the amino terminal C2 domain of most mammalian forms of PKCɛ; selectively and reversibly inhibits the translocation of PKCɛ to intracellular membranes, blocking activation
