Virginiamycin complex (Item No. 14503) contains two antibiotics, virginiamycin M1 (Item No. 9002172) and virginiamycin S1. Virginiamycin S1 is a macrolide antibiotic. It is a member of the streptogramin B group of antibiotics, which bind the 50S ribosomal subunit at the peptidyl transferase center to inhibit initiation and translocation.{27765} They show good bactericidal activity against methicillin-resistant S. aureus (MRSA), although resistance in MRSA is conferred by the cfr gene.{27765,28231} Virginiamycin S1 acts synergistically with virginiamycin M1 to irreversibly inhibit protein synthesis in bacteria.{23008}
产品描述
A macrolide antibiotic that shows good bactericidal activity against MRSA
