Chrysin is a natural flavonoid with antioxidant, anti-inflammatory, and anticancer properties. It blocks COX-2 gene expression, PGE2 production, and hydroxyl radical formation in LPS-induced RAW 264.7 cells.{28408,28409} Chrysin inhibits insulin-induced HIF-1α expression (~50% at 10 µM) in human prostate cancer DU145 cells and blocks DU145 xenograft-induced angiogenesis in vivo.{28410} In a mouse model of ischemia/reperfusion injury, chrysin decreased pro-inflammatory gene expression and oxidative stress, resulting in a reduction of infarct volume and neurological defects.{28411}
产品描述
A natural flavonoid with antioxidant, anti-inflammatory, and anticancer properties; inhibits HIF-1α expression in cancer cells; decreases pro-inflammatory gene expression and oxidative stress in ischemia/reperfusion injury
