Esomeprazole, the (S)-enantiomer of omeprazole (Item No. 14880), is a selective inhibitor of the gastric H+/K+ ATPase.{18249} It is highly effective at inhibiting gastric acid secretion and demonstrates lower first-pass hepatic metabolism and slower plasma clearance, resulting in increased bioavailability compared to omeprazole.{18249,28643} Esomeprazole is predominantly metabolized by the cytochrome P450 (CYP) isomer CYP3A4.{18249}
产品描述
The (S)-enantiomer of omeprazole, a selective inhibitor of the gastric H+/K+ ATPase that demonstrates increased bioavailability compared to omeprazole
