Pristanic acid is a natural terpenoid acid present at micromolar concentrations in the plasma of healthy individuals. It is obtained from dietary sources or by the α-oxidation of phytanic acid (Item No. 90360), which occurs predominantly in peroxisomes.{28841,28842} Pristanic acid is an agonist of PPARα (EC50 = 40 µM).{28843} It is also a substrate of the mammalian peroxisomal ATP-binding cassette (ABC) transporter ABCD3, which facilitates its delivery into peroxisomes for β-oxidation.{28840}
产品描述
A natural terpenoid acid present at micromolar concentrations in the plasma of healthy individuals; an agonist of PPARα (EC50 = 40 µM); a substrate of the mammalian peroxisomal transporter ABCD3, which facilitates its delivery into peroxisomes for β-oxidation
