- 中文名称
9-氨基喜树碱
- 英文名字
- 9-amino Camptothecin
- 供应商
- Cayman Chemical
- 产品货号
- 17232-10
- 产品报价
- ￥询价/10mg
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- DNA topoisomerases relax supercoiled DNA during replication, transcription, recombination, repair, and chromosome condensation. The relaxation of DNA supercoiling by topoisomerase I at single-strand breaks represents a target for anticancer agents to intercalate between DNA base pairs, leading to the activation of apoptotic and cell cycle arrest pathways.{21116} 9-amino Camptothecin is a topoisomerase I inhibitor that was developed as a more water-soluble analog of camptothecin (Item No. 11694).{21114,21115} It is cytotoxic to HT-29 cells at an IC50 value of 19 nM, induces DNA damage in whole cells at a concentration of 85 nM, and demonstrates significant anti-tumor activity in clinical studies.{21114,21115}
- 产品描述
- A topoisomerase I inhibitor that is cytotoxic to HT-29 cells (IC50 = 19 nM), induces DNA damage in whole cells (at 85 nM), and demonstrates significant anti-tumor activity
- 产品形式
- 晶体
- 保存建议
- 建议您在收到Cayman Chemical品牌的9-氨基喜树碱 (10 mg)产品后置于-20℃保存.
- 其他
- Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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