5(6)-Carboxyfluorescein is a mixture of 5-carboxy and 6-carboxy derivatives of fluorescein. It is commonly used to label biomolecules through a reaction involving the carboxyl group.{13893} Unlike its succinimidyl ester derivative CFSE (Item No. 14456), 5(6)-carboxyfluorescein is membrane impermeant. As a result, it can be used in studies of membrane permeability.{24235} 5(6)-Carboxyfluorescein displays excellent fluorescence (excitation/emission at 492/514 nm, respectively), and its excitation maximum closely matches the 488 nm spectral line of argon-ion lasers.
产品描述
A mixture of 5-carboxy and 6-carboxy derivatives of fluorescein; used to label biomolecules through a reaction involving the carboxyl group; membrane impermeant, with applications in studies of membrane permeability
