Amphomycin is a natural antibacterial lipopeptide first isolated from S. canus. Lipopeptides are cyclic depsipeptides with a peptidyl side chain capped with a saturated alkyl tail.{27765} They preferentially target Gram-positive bacteria and may be useful against drug resistant strains.{27765} Amphomycin is also an inhibitor of peptidoglycan synthesis in both bacterial and mammalian systems, as it binds with phosphorylated substrates in a calcium-dependent manner.{27780,27781,27782,27779}
产品描述
An antibacterial lipopeptide that targets Gram-positive bacteria and may be useful against drug resistant strains; also inhibits peptidoglycan synthesis