Cell-permeable. Directs differentiation of embryonic stem cells (ESCs) into the endodermal lineage (EC₅₀=125nm). Nodal/Smad signaling is activated indicating IDE-1 functions via TGF-b-signaling pathway.Formula:C15H18N2O5Solubility:DMSO (~25mg/ml), EtOH (~12mg/ml with warming)Molecular Weight: ~306.31Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
