Cell-permeable. A potent ferroptosis (an iron-dependent form of non-apoptotic cell death) inhibitor. Inhibits erastin-induced ferroptosis in HT-1080 cells with an EC50 of 60nm. Ferrostatin-1 inhibits ferroptosis in cancer cells as well as blocks glutamate-induced cell death in organotypic rat brain slices.Formula:C15H22N2O2Solubility:DMSO (100mM)Molecular Weight: ~262.35Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
