Cyt387 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC50 values of 11nM and 18nM, respectively. Inhibits JAK3 at much higher concentrations (IC50 = 155nM).Solubility:DMSO (~80mg/ml) or Ethanol (<1mg/ml)PubChem CID: 25062766MDL Number: MFCD16038899Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
