- 中文名称
Cicaprost (10 mg)
- 英文名字
- ZK 9648, Cicaprost, 2-[2-[(2E,3aS,4S,5R,6aS)-hexahydro-5-hydroxy-4-[(3S,4S)-3-hydroxy-4-methyl-1,6-nonadiyn-1-yl]-2(1H)-pentalenylidene]ethoxy]-acetic acid
- 供应商
- Cayman
- 产品货号
- 16831-10
- 产品报价
- ￥35868/10 mg
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- Prostaglandin I2 -PGI2, prostacyclin) is the most potent endogenous vasodilator that affects both the systemic and pulmonary circulation. Cicaprost is a PGI2 analog that is orally active with prolonged availability in vivo, having a terminal half life in plasma of one hour. In addition to their effects on smooth muscle, PGI2 analogs, including cicaprost, have been shown to inhibit the pro-inflammatory actions of certain leukocytes, suppress cardiac fibrosis, and block mitogenesis of certain cell types. Importantly, cicaprost has been shown to strongly reduce lung and lymph node metastasis in rats, suggesting that it might be useful in cancer therapy.
- 产品描述
- A prostacyclin analog that is orally active with prolonged availability in vivo, having a terminal half-life in plasma of one hour; inhibits the pro-inflammatory actions of certain leukocytes, suppresses cardiac fibrosis, and blocks mitogenesis of certain cell types
- 产品形式
- 保存建议
- -20
- 其他
- Cayman Chemical
- 注意
-
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