- 中文名称
PNU 10483 |β-GPA; N-(氨基亚氨基甲基)-β-丙氨酸
- 英文名字
- PNU 10483|β-GPA; N-(aminoiminomethyl)-β-alanine
- 供应商
- Cayman Chemical
- 产品货号
- 16725-1
- 产品报价
- ¥询价/1g

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- 3-Guanidinopropionic acid is a creatine analog that alters skeletal muscle energy expenditure. It reduces cellular ATP, creatine, and phosphocreatine levels and stimulates AMP-activated protein kinase (AMPK), activating PPARγ coactivator 1α (PGC-1α).{27453,27454,27456,27452} PGC-1α activation results in enhanced expression of AMPK, as well as genes for oxidative phosphorylation, electron transport chain, and mitochondrial biogenesis, increasing oxidative muscle fibers, numbers of mitochondria, and motor performance.{27453,27455} 3-Guanidinopropionic acid evokes a shift from glycolytic to oxidative metabolism, increased cellular glucose uptake, and increased fatigue tolerance.{27454} In aged rats, reduced mitochondrial biogenesis in response to chronic activation of AMPK with 3-guanidinopropionic acid leads to metabolic insufficiency that can contribute to muscle loss.{27457,27455}
- 产品描述
- A creatine analog that alters skeletal muscle energy expenditure; reduces cellular ATP, creatine, and phosphocreatine levels and stimulates AMPK, activating PGC-1α; increases the expression of genes for oxidative phosphorylation, electron transport chain, and mitochondrial biogenesis
- 产品形式
- A crystalline solid
- 保存建议
- 建议您在收到Cayman Chemical品牌的3-Guanidinopropionic Acid (1 g)产品后置于-20度保存,产品有效期为730天.
- 其他
- Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒,其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒,如:类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等;也提供多种高质量试剂,包括:类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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