- 中文名称
Darapram | Daraprim | Khloridin | NSC 3061；5,4-氯苯基-6-乙基-2,4-嘧啶二胺
- 英文名字
- Darapram|Daraprim|Khloridin|NSC 3061; 5,4-chlorophenyl-6-ethyl-2,4-pyrimidinediamine
- 供应商
- Cayman Chemical
- 产品货号
- 16472-100
- 产品报价
- ￥询价/100mg
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Pyrimethamine is an antiprotozoal agent that is primarily active against P. falciparum, inhibiting the protozoal enzyme dihydrofolate reductase (DHFR).{26927} By blocking DHFR activity, pyrimethamine prevents the production of tetrahydrofolic acid, an essential coenzyme involved in DNA and RNA synthesis. In in vivo antimalarial mouse models, pyrimethamine displays a prophylactic effect at an ED50 value of 0.5 mg/kg.{26925} Sulphonamides act synergistically with pyrimethamine by arresting production of dihydrofolic acid, resulting in the sequential blockade of the folate pathway of protozoa.{26897} Pyrimethamine has also been found to limit the expression of the superoxide dismutase 1 gene, a protein involved in amyotrophic lateral sclerosis.{26926}
- 产品描述
- A dihydrofolate reductase inhibitor that prevents the production of tetrahydrofolic acid in P. falciparum and other protozoa; displays a prophylactic effect (ED50 = 0.5 mg/kg) in in vivo antimalarial mouse models
- 产品形式
- A crystalline solid
- 保存建议
- 建议您在收到Cayman Chemical品牌的Pyrimethamine (100 mg)产品后置于-20度保存，产品有效期为730天.
- 其他
- Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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