中文名称

Rh-PG |若丹明苯乙二醛；3'，6'-双（二甲基氨基）-3-氧代-N-（（1-（1-氧代-1-（（3-（2-氧代乙酰基）苯基）氨基）丙烷-2-基）-1H- 1,2,3-三唑-4-基）甲基）-3H-螺[异苯并呋喃-1,9'-x吨] -5-羧酰胺水合物

英文名字

Rh-PG|Rhodamine Phenylglyoxal; 3',6'-bis(dimethylamino)-3-oxo-N-((1-(1-oxo-1-((3-(2-oxoacetyl)phenyl)amino)propan-2-yl)-1H-1,2,3-triazol-4-yl)methyl)-3H-spiro[isobenzofuran-1,9'-xanthene]-5-carboxamide hydrate

供应商

Cayman Chemical

产品货号

16172-500

产品报价

￥询价/500ug

产品说明书

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购买方式

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产品新闻

背景资料

Protein arginine deiminases (PADs) catalyze the posttranslational modification of arginine residues on proteins to form citrulline, which plays a large role in regulating gene expression.{18134} Abnormally high PAD activity has been observed in a host of human diseases.{18134,18137} Citrulline-specific probe is a highly sensitive, rhodamine phenylglyoxal-based fluorophore that specifically detects protein citrullination via a chemoselective reaction between glyoxal and citrulline.{26196} This chemical probe (comprised of a single isomer) is capable of reacting with any citrulline-containing protein and can be analyzed with fluorescent imaging (excitation 532 nm; emission 580 nm).{26196} When added at 100 µM for 30 minutes at acidic pH, this probe has a reported limit of detection of ~10 ng for citrullinated histone H3 and ~1 ng for autodeiminated PAD4.{26196}

产品描述

A highly sensitive, rhodamine phenylglyoxal-based fluorophore that specifically detects protein citrullination via a chemoselective reaction between glyoxal and citrulline; reacts with any citrulline-containing protein and can be analyzed with fluorescent imaging (Ex. 532 nm; Em. 580 nm); limit of detection of ~10 ng for citrullinated histone H3 and ~1 ng for autodeiminated PAD4 when applied at 100 µM for 30 minutes at acidic pH

产品形式

A solution in dimethyl formamide

保存建议

建议您在收到Cayman Chemical品牌的Citrulline-specific Probe (500 µg)产品后置于-20度保存，产品有效期为365天.

其他

Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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