While extracellular glutamic acid is an excitatory neurotransmitter, intracellular glutamic acid is an amino acid that serves numerous metabolic roles, including as a precursor for α-ketoglutarate.{24138} 5-Octyl D-glutamate, also known as 5-octyl ester D-glutamate, is a stable, cell-permeable molecule that generates free D-glutamate upon hydrolysis of the ester bond by cytoplasmic esterases. It may be used in experiments to increase levels of cytoplasmic D-glutamate. This compound is useful in studies examining the cellular effects of 5-octyl L-glutamate (Item No. 16107) or 5-octyl α-ketoglutarate.{26069}
产品描述
A stable, cell-permeable molecule that generates free D-glutamate upon hydrolysis of the ester bond by cytoplasmic esterases; used in experiments to increase levels of cytoplasmic D-glutamate, or in studies examining the cellular effects of 5-octyl D-glutamate or 5-octyl α-ketoglutarate
