中文名称

6-TG | NSC 752 | NSC 76504；2-氨基-1,9-二氢-6H-嘌呤-6-硫酮

英文名字

6-TG|NSC 752|NSC 76504; 2-amino-1,9-dihydro-6H-purine-6-thione

供应商

Cayman Chemical

产品货号

15774-500

产品报价

￥询价/500mg

产品说明书

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购买方式

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产品新闻

背景资料

6-Thioguanine (6-TG) is a thio analog of the purine base guanine that incorporates into DNA during replication, inducing double-strand breaks that destabilize its structure and result in cytotoxicity.{25754,25756} Upon incorporation into DNA, 6-TG has been shown to disrupt cytosine methylation by DNA methyltransferases, interfering with the epigenetic pathway of gene regulation.{25757,25758} This compound has been used as a chemotherapeutic for acute leukemia and other types of cancer, including BRCA2-mutated tumors.{25755}

产品描述

A thio analog of the purine base guanine that incorporates into DNA during replication, inducing double-strand breaks that destabilize its structure and result in cytotoxicity; used as a chemotherapeutic for acute leukemia and other types of cancer, including BRCA2-mutated tumors

产品形式

A crystalline solid

保存建议

建议您在收到Cayman Chemical品牌的6-Thioguanine (500 mg)产品后置于-20度保存，产品有效期为730天.

其他

Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

注意

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