中文名称

囊性纤维化跨膜电导调节剂抑制剂II | GlyH-101; 2-[（（3,5-二溴-2,4-二羟基苯基）亚甲基]酰肼N-2-萘基-甘氨酸

英文名字

Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor II|GlyH-101; 2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide N-2-naphthalenyl-glycine

供应商

Cayman Chemical

产品货号

15772-5

产品报价

￥询价/5mg

产品说明书

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购买方式

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产品新闻

背景资料

The cystic fibrosis (CF) gene encodes a cAMP-regulated chloride channel, the CF transmembrane conductance regulator (CFTR).{25612} CFTR inhibitor II, also known as GlyH-101, is a glycine hydrazide that selectively and reversibly blocks the CFTR channel (Ki = 4.3 µM).{25797,25798} This compound binds to a site at the external pore of CFTR, occluding the pore and rapidly preventing chloride transport.{25797,25798} Intraluminal CFTR inhibitor II greatly reduces intestinal fluid secretion induced by cholera toxin.{25798} It is effective in cells in culture and also in nasal and intestinal epithelia in vivo.{25794,25793,25795,25796}

产品描述

Selectively and reversibly blocks the CFTR channel (Ki = 4.3 µM); reduces intestinal fluid secretion induced by cholera toxin; effective in cells in culture and also in nasal and intestinal epithelia in vivo

产品形式

A crystalline solid

保存建议

建议您在收到Cayman Chemical品牌的CFTR Inhibitor II (5 mg)产品后置于-20度保存，产品有效期为730天.

其他

Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

注意

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