Thaxtomin A is a major phytotoxin produced by S. scabies, gram-positive soil bacterium responsible for producing scabs on tubers and root vegetables.{25529} This bacterial metabolite acts as a virulence factor in the common scab potato disease and demonstrates herbicidal activity against the dicotyledon weeds B. campestris and A. retroflexus.{25530}
产品描述
A cyanoquinoline that irreversibly inhibits the receptor tyrosine kinases EGFR (IC50 = 39 nM) and HER2 (IC50 = 1.2 μM); disrupts Akt and MAPK pathways, inducing apoptosis and suppressing the growth of tumor cell lines
