Indolmycin is an antibiotic isolated from various Streptomyces strains that functions by competitively inhibiting the prokaryotic tryptophanyl-tRNA synthetase (IC50 = 30 μM) without significantly affecting the corresponding eukaryotic synthetase.{24924,24923} It exhibits antibacterial activity against mupirocin- and fusidic acid-resistant strains of Staphylococci.{24922}
产品描述
An antibiotic that competitively inhibits the prokaryotic tryptophanyl-tRNA ligase (IC50 = 30 μM); exhibits antibacterial activity against mupirocin- and fusidic acid-resistant strains of Staphylococci