- 中文名称
NSC 285116；N-[（7R，8S）-2-羧基-7,8-二氢-8-羟基-4-[（1S）-1-羟乙基] -7-喹啉基] -L-戊基-2,3-二氢芳基- 2,3-didehydroalanyl-L-alanyl-2-[（（4aR，11S，14Z，18S，21S，28S，32aS）-4a-amino-21-[（1S，2R）-1,2-dihydroxy-1-甲基丙基] -14-亚乙基-3,4,4a，
- 英文名字
- NSC 285116; N-[(7R,8S)-2-carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-L-valyl-2,3-didehydroalanyl-2,3-didehydroalanyl-L-alanyl-2-[(4aR,11S,14Z,18S,21S,28S,32aS)-4a-amino-21-[(1S,2R)-1,2-dihydroxy-1-methylpropyl]-14-ethylidene-3,4,4a,9,10,11,12,13,14,18,19,20,21,27,28,32a-hexadecahydro-11,28-bis[(1R)-1-hydroxyethyl]-9,12,19,26-tetraoxo-17H,26H-8,5:18,15:25,22:32,29-tetranitrilo-5H,15H-pyrido[3,2-m][1,11,17,24,4,7,20,27]tetrathiatetraazacyclotriacontin-2-yl]-4-thiazolecarbonyl-2,3-didehydroalanyl-2,3-didehydro-(1→528)-lactone-alaninamide
- 供应商
- Cayman Chemical
- 产品货号
- 15378-500
- 产品报价
- ￥询价/500ug
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- The mammalian transcription factor forkhead box M1 (FoxM1) is induced during G1 phase, with expression continuing through S phase and mitosis. Siomycin A is a peptide thiazole antibiotic, first isolated from S. sioyaensis, that interacts with the 23S rRNA of bacteria.{24927} It inhibits FoxM1 (IC50 = ~ 5 μM), preventing the expression of FoxM1-regulated genes, which includes FoxM1 itself.{24928,24931} Through this mechanism, siomycin A prevents proliferation and induces apoptosis in certain types of stem cells as well as cancer cells.{24930,24926,24929}
- 产品描述
- A peptide thiazole antibiotic that inhibits FoxM1 (IC50 = ~ 5 μM), preventing the expression of FoxM1-regulated genes; prevents proliferation and induces apoptosis in certain types of stem cells as well as cancer cells
- 产品形式
- A white solid
- 保存建议
- 建议您在收到Cayman Chemical品牌的Siomycin A (500 µg)产品后置于-20度保存，产品有效期为730天.
- 其他
- Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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