- 中文名称
N-（9,10-二氢-9,10-二氧-2--2-菲基）-2,2-二甲基丙酰胺
- 英文名字
- N-(9,10-dihydro-9,10-dioxo-2-phenanthrenyl)-2,2-dimethyl-propanamide
- 供应商
- Cayman Chemical
- 产品货号
- 15368-5
- 产品报价
- ￥询价/5mg
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Phosphatase and tensin homology on chromosome 10 (PTEN) functions as a key regulatory enzyme in many signal transduction pathways by dephosphorylating proteins and lipids including Akt and phosphatidylinositol 3,4,5-trisphosphate (PIP3). SF1670 specifically binds to the active sight of PTEN inhibiting its activity with an IC50 value of 2 μM.{24903,14756} At nanomolar concentrations it increases cellular PIP3 levels, phosphorylation of Akt, and glucose uptake in adipocytes.{14756,24902} Pretreatment with SF1670 has been used to enhance PIP3 signaling in transplanted neutrophils, augmenting their function at sites of infection in neutropenic recipient mice.{24902}
- 产品描述
- Inhibits PTEN activity (IC50 = 2 μM), increasing cellular PIP3 levels, phosphorylation of Akt, and glucose uptake in adipocytes; used to enhance PIP3 signaling in transplanted neutrophils
- 产品形式
- A dark purple solid
- 保存建议
- 建议您在收到Cayman Chemical品牌的SF1670 (5 mg)产品后置于4度保存，产品有效期为180天.
- 其他
- Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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