- 中文名称
IL-2 Receptor, alpha, Human, BioAssay Kit (CD25, IL2RA)
- 英文名字
- IL-2 Receptor, alpha, Human, BioAssay Kit (CD25, IL2RA)
- 供应商
- USBiological
- 产品货号
- 145748
- 产品报价
- ￥1/1Kit
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！
- 产品描述
- The biological effects of interleukin 2 (IL-2) are mediated by its binding to a multi-chain cellular receptor complex. The IL-2 receptor (IL-2 R) complex consists of three glycoprotein chains. The alpha chain (IL-2 R alpha /CD25) and beta chain (IL-2 R beta /CD122) act together with the gamma chain (IL-2 R gamma /CD132) to form a high affinity receptor that transduces the signal upon IL-2 binding. Alone, IL-2 R alpha binds IL-2 with low affinity, but is unable to transduce a signal. The alpha/beta combination binds IL-2 with intermediate affinity, but is still unable to transmit a signal inside the cell. The beta/gamma complex has intermediate affinity and is capable of signaling if the concentration of IL-2 is relatively high. A soluble form of IL-2 R alpha is present in the serum in parallel with its increased cellular expression. There are reports of soluble IL-2 R beta as well. The biologic function of soluble IL-2 R alpha is unclear because, due to its low affinity, it is expected to be a poor inhibitor of IL-2. IL-2 R alpha is a precursor type I membrane protein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. Studies suggest a correlation between the levels of IL-2 R alpha in serum with the onset of rejection in allograft recipients, with autoimmune disease activation in rheumatoid arthritis and systemic lupus erythematosis patients and with the course of some leukemias and lymphomas.Sample Type:Cell culture supernates, serum, EDTA plasma, and heparin plasma.Sensitivity:The mean MDD was 0.45pg/ml. The Minimum Detectable Dose (MDD) was determined by adding two standard deviations to the MFI of twenty zero standard replicates and calculating the corresponding concentration. Range:~0.24-0.76pg/mlSpecificity:Recognizes natural and recombinant human IL-2 Ra. Test Principle:Human IL-2 R alpha BioAssay Kit afford the user the benefit of multianalyte analysis of biomarkers in a complex sample. For each sample type, a single, multipurpose diluent is used to optimize recovery, linearity, and reproducibility. Such a multipurpose diluent may not optimize any single analyte to the same degree that a unique diluent selected for analysis of that analyte can optimize conditions. Therefore, some performance characteristics may be more variable than those for assays designed specifically for single analyte analysis.Kit Components:Microparticle Concentrate, 100X concentrated, 1x0.075mlBiotin-Antibody Concentrate, 100X concentrated, 1x0.075mlStorage and Stability:Store powder at 4°C. Store other components at 4°C. Stable for at least 6 months For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- 产品特点
- 针对IL-2 Receptor, alpha, Human, BioAssay Kit (CD25, IL2RA)该产品的特点优势，欢迎查阅官网提供的产品说明书。
- 保存建议
- 建议收到IL-2 Receptor, alpha, Human, BioAssay Kit (CD25, IL2RA)产品后将其置于4°C保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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