Inhibitor of Smoothened (Smo) signaling via a unique mechanism. Inhibits Shh-induced accumulation of Smo::EGFP fusion protein in the primary cilium (IC50 = 1.1um). Inhibits both wild-type Smo and an oncogenic form (SmoM2) with similar efficacy.Formula:C16H23BrN2O.HClSolubility:DMSO (~100mM), H2O (~20mM), Ethanol (~20mM)Molecular Weight:~375.73Storage and Stability:Store at RT. Stable for 12 months.