High affinity, competitive 5-HT and norepinephrine (NE) re-uptake inhibitor (Ki values are 8.5 and 45nm for 5-HT and NE reuptake respectively in cortical synaptosomes; IC50 values are 28 and 46nm for 5-HT and NE reuptake respectively in rat hippocampal slices). Also blocks dopamine reuptake (Ki=300nm in striatal synaptosomes). Exhibits antidepressant and anxiolytic effects. Orally bioavailable.Formula:C18H19NOS.HClSolubility:DMSO (~100mM), H2O (~10mM) with gentle warmingMolecular Weight:~333.88Storage and Stability:Store at RT. Stable for 12 months.
产品形式
该产品为类白色固体。
保存建议
接收到(S)-Duloxetine Hydrochloride (Potent 5-HT and NA Reuptake Inhibitor, Blocks Dopamine Reuptake, (+)-(S)-N-Methyl-3-(1-naphthyloxy)- 3-(2-thienyl)propanamine hydrochloride)产品后,置于室温温度下保存。