Carmofur is a fluorinated pyrimidine and derivative of fluorouracil (Item No. 14416). It has anti-neoplastic activity and is commonly used as adjuvant therapy following resection for some forms of cancer.{28065} Recent studies have shown that carmofur is a potent inhibitor of acid ceramidase (IC50 = 29 nM), an enzyme that is over-expressed in some tumors.{22147,22982}
产品描述
A fluorinated pyrimidine and derivative of fluorouracil that has anti-neoplastic activity and is commonly used as adjuvant therapy following resection for some forms of cancer; a potent inhibitor of acid ceramidase (IC50 = 29 nM)
