中文名称

GSK2801

英文名字

GSK2801

供应商

Cayman Chemical

产品货号

14120-1

产品报价

￥询价/1mg

产品说明书

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购买方式

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产品新闻

背景资料

BAZ2A/B are bromodomain-containing proteins whose biological function is believed to function similarly to ACF1, the Drosophila BAZ2B ortholog. ACF complexes play roles in establishing regular nucleosome spacing during chromatin assembly and influencing different remodeling outcomes at target loci.{21672,21674} BAZ2A and BAZ2B constitute the central scaffolding protein of the nucleolar remodeling complex (NoRC) that regulates the expression of noncoding RNAs. GSK2801 is a selective, cell-permeable inhibitor of the BAZ2 family of bromodomain-containing proteins (IC50s = 9-350 nM in a BAZ2B AlphaScreen).{29090,26201} It binds to BAZ2A and BAZ2B with Kd values of 0.26 and 0.14 µM, respectively, and does not interact with the bromodomains of BRD4(BD1), CREBBP, TRIM24/TIF1α, PB1(BD5), PCAF, or ATAD2.{29090,26201} See the Structural Genomics Consortium (SGC) website for more information.

产品描述

A selective, cell-permeable inhibitor of the BAZ2 family of bromodomain containing proteins (IC50s = 9-350 nM in a BAZ2B AlphaScreen; KDs = 0.26 and 0.14 µM, for BAZ2A and BAZ2B respectively)

产品形式

晶体

保存建议

建议您在收到Cayman Chemical品牌的GSK2801 (1 mg)产品后置于-20℃保存.

其他

Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

注意

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