- 中文名称
11-脱氧PGE1;9-氧代-15S-羟基-脯氨酸-13E-en-1-油酸
- 英文名字
- 11-deoxy PGE1; 9-oxo-15S-hydroxy-prost-13E-en-1-oic acid
- 供应商
- Cayman Chemical
- 产品货号
- 13510-5
- 产品报价
- ¥询价/5mg

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- 11-deoxy Prostaglandin E1 (11-deoxy PGE1) is a synthetic analog of PGE1. Early reports show that it is a selective agonist for the EP2 receptor but effective at much higher concentrations than PGE2.{1360,1026} However, later studies show that it is a non-selective agonist of EP receptors and stimulates cAMP release in Jurkat cells with an EC50 of 0.25 µM.{2120} 11-deoxy PGE1 also exhibits vasodepressor and bronchodilator responses in guinea pigs.{2217} 11-deoxy PGE1 exhibits selectively for the mouse EP3 receptor and is essentially equipotent to PGE1 at this receptor subtype. The Ki values for binding to the mouse EP1, EP2, EP3, and EP4 receptors are 600, 45, 1.1, and 23 nM, respectively.{6640}
- 产品描述
- 11-deoxy PGE1 is a synthetic analog of PGE1. Early reports show that it is a selective agonist for the EP2 receptor but effective at much higher concentrations than PGE2.{1360,1026} However, later studies show that it is a non-selective agonist of EP receptors and stimulates cAMP release in Jurkat cells with an EC50 of 0.25 µM.{2120} 11-deoxy PGE1 also exhibits vasodepressor and bronchodilator responses in guinea pigs.{2217} 11-deoxy PGE1 exhibits selectively for the mouse EP3 receptor and is essentially equipotent to PGE1 at this receptor subtype. The Ki values for binding to the murine EP1, EP2, EP3, and EP4 receptors are 600, 45, 1.1, and 23 nM, respectively.{6640}
- 产品形式
- A crystalline solid
- 保存建议
- 建议您在收到Cayman Chemical品牌的11-deoxy Prostaglandin E1 (5 mg)产品后置于-20度保存,产品有效期为730天.
- 其他
- Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒,其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒,如:类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等;也提供多种高质量试剂,包括:类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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