中文名称

2,3-dinor Prostaglandin E1 (1 mg)

英文名字

2,3-dinor PGE1, 2,3-dinor Prostaglandin E1, 9-oxo-11.alpha.,15S-dihydroxy-2,3-dinor-prost-13E-en-1-oic acid

供应商

Cayman

产品货号

13120-1

产品报价

￥16856/1 mg

产品说明书

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产品新闻

背景资料

Prostaglandin E1 -PGE1) is not a major naturally occurring prostaglandin, but it is widely administered clinically for several indications including peripheral occlusive vascular disease, erectile dysfunction and in neonatal cardiology. The metabolism of PGE1 is normally initiated by oxidation at C-15, resulting in 13,14-dihydro-15-keto PGE1 as the major metabolite. However, inhibition of this pathway or saturation by excess substrate could theoretically lead to enhanced production of 2,3-dinor metabolites, including 2,3-dinor PGE1. The biological activity of 2,3-dinor PGE1 has not been published. Cayman Chemical is a leading supplier of prostaglandins and their metabolites, and is currently the exclusive manufacturer of 2,3-dinor PGE1.

产品描述

PGE1 is not a major naturally occurring prostaglandin, but it is widely administered clinically for several indications including peripheral occlusive vascular disease, erectile dysfunction, and in neonatal cardiology.{22,3803} The metabolism of PGE1 is normally initiated by oxidation at C-15, resulting in 13,14-dihydro-15-keto PGE1 as the major metabolite. However, inhibition of this pathway or saturation by excess substrate could theoretically lead to enhanced production of 2,3-dinor metabolites, including 2,3-dinor PGE1. The biological activity of 2,3-dinor PGE1 has not been published.

产品形式

保存建议

-20

其他

Cayman Chemical

注意

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