Withanolide A is a natural product isolated from the medicinal plant W. somnifera that has antioxidant and neuroprotective activity.{28425} It helps to promote neurite outgrowth at 1 µM in cultured neurons and in rodents injected with Aβ(25-35), and also recovers Aβ(25-35)-induced memory deficit in mice (10 µmol/kg/day).{28426,28427} Withanolide A reverses hypoxia-mediated neurodegeneration by restoring hypoxia-induced glutathione depletion in the hippocampus of mice.{28428}
产品描述
A natural product that has antioxidant and neuroprotective activity; promotes neurite outgrowth in cultured neurons and in rodents injected with Aβ(25-35); recovered Aβ(25-35)-induced memory deficit in mice; reverses hypoxia-mediated neurodegeneration by restoring hypoxia induced glutathione depletion in the hippocampus
