Hypophyllanthin is an active principle of P. amarus, a plant studied for its potential to treat hepatotoxicity.{28462} In Caco-2 cells 100 µM hypophyllanthin has been shown to reversibly inhibit P-glycoprotein (also known as multidrug resistance protein 1 (MDR1)) function without effect on MDR2 activity.{28463}
产品描述
An active principle of P. amarus that has been shown to reversibly inhibit P-glycoprotein (also known as multidrug resistance protein 1 (MDR1)) function without effect on MDR2 activity