Ostarine is a non-steroidal selective androgen receptor modulator that binds the androgen receptor with a Ki value of 3.8 nM in vitro.{24834} At a dose of 0.03 mg/day in castrated male rats, ostarine showed anabolic effects selective for bone and muscle tissue while demonstrating limited effects on other androgen-responsive tissues including prostate and seminal vesicles.{24834} In a phase II clinical trial ostarine displayed a dose-dependent improvement in total lean body mass and physical function in patients with cancer-associated cachexia (muscle wasting).{24833}
产品描述
A non-steroidal SARM (Ki = 3.8 nM in vitro) with anabolic effects selective for bone and muscle tissue while demonstrating limited effects on other androgen-responsive tissues including prostate and seminal vesicles