HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Classical human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules, the non-classical by e.g. HLA-E, HLA-G.
应用类型
FC (QC tested), WB, IHC(F)
免疫原
IFN-gamma-treated human melanoma cells Colo 38
来源宿主
小鼠
反应性
Human
保存建议
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.