Helios, also known as IKZF2 (Ikaros family zinc finger protein 2) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development, together with other members of this family, such as Aiolos and Ikaros. Helios forms homo- and heterodimers with these proteins and is thought to function predominantly in early hematopoietic development. Expression of Helios, Aiolos and Ikaros is restricted to cells of the hematopoietic system, whereas other family members, Eos and Pegassus, are more widely expressed. Helios is expressed at early stages of thymocyte development. In mature T cells, Helios has been strongly associated with Treg cells.
应用类型
FC (QC tested)
免疫原
Peptide coresponding to the amino acids 51-107 of Helios
来源宿主
亚美尼亚仓鼠
反应性
Mouse, Human
保存建议
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
