Nitrotyrosine can be detected in proteins from a variety of tissues usually in association with pathological conditions. Reaction of nitric oxide with superoxide produces peroxynitrite, which can undergo heterolytic cleavage into nitronium and hydroxyl ions. Nitration of tyrosine residues by nitronium ion forms nitrotyrosine groups in the respective proteins. Nitrotyrosine is thus a marker for inflammation-associated tissue damage.
应用类型
WB, IHC(P), IHC(F)
免疫原
NO2-Tyr-CH2-Thyroglobulin
来源宿主
小鼠
反应性
Species independent
保存建议
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
