NTAL (Non-T cell activation linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
应用类型
WB
免疫原
Recombinant N-terminal cytoplasmic domain (aa 124-203) of mouse NTAL.
来源宿主
兔
反应性
Mouse
保存建议
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
