CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
应用类型
FC (QC tested), IP, WB
免疫原
Human granulocytes
来源宿主
小鼠
反应性
Non-human primates, Human
保存建议
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
