The T cell receptor (TCR)/CD3 complex consists of two variable antigen-recognition receptor chains (TCR-alpha/TCR-beta or TCR-gamma/TCR-delta) that are non-covalently linked to at least four different invariant chains: CD3 gamma, CD3 delta, CD3 epsilon, and the CD3 zeta chain that exists as either a homodimer or as a heterodimer with its splice-variant the CD3 eta chain. The CD3 complex functions to transduce intracellular signals during TCR antigen recognition. CD3 is expressed early in thymocyte development, and on a subset of NK cells. CD3 epsilon is one of at least three invariant proteins that associate with the variable antigen recognition chains of the T cell receptor and function in signal transduction.
应用类型
IHC, FC, IP
免疫原
该Anti-Mouse CD3的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Mouse CD3的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Mouse CD3的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Mouse CD3的详细信息查看ReliaTech提供的产品说明书。溶解建议:Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.