- 中文名称
Anti-Mouse Frizzled-2
- 英文名字
- Anti-Mouse Frizzled-2
- 供应商
- ReliaTech
- 产品货号
- 103-M386
- 产品报价
- ￥询价/100ug
- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻
- 背景资料
- Wnt signaling is involved in variety of developmental processes including cell fate determination, cell polarity, tissue patterning and control of cell proliferation. Members of the Frizzled family of proteins serve as receptors for the Wnt signaling pathway. The founding member of this family was identified in Drosophila based on its role in tissue polarity in the adult cuticle and named for the disorganized appearance of bristle hairs on the mutant. Ten mammalian Frizzled genes have been identified to date. The predicted structure of Frizzled proteins is similar among all family members, containing a divergent Nterminal signal peptide, a highly conserved extracellular cysteinerich domain, a variablelength linker region, a sevenpass transmembrane domain, and a variablelength C-terminal tail. One of the most conserved regions of the Frizzled proteins is the extracellular cysteine-rich domain (CRD) which spans approximately 120 AA and contains 10 invariant cysteines. Mouse Frizzled-2 shows 100% amino acid identity to human and rat Frizzled2 in the CRD region. Frizzled2 expression is greater in embryonic than adult tissues, with heart, brain, lung, kidney and gut showing the highest levels.
- 应用类型
- WB
- 免疫原
- 该Anti-Mouse Frizzled-2的详细信息查看ReliaTech提供的产品说明书。
- 来源宿主
- 该Anti-Mouse Frizzled-2的详细信息查看ReliaTech提供的产品说明书。
- 反应性
- 该Anti-Mouse Frizzled-2的详细信息查看ReliaTech提供的产品说明书。
- 保存建议
- 该Anti-Mouse Frizzled-2的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
- 其他
- ReliaTech全称为受体配体技术有限公司 (Receptor Ligand Technologies GmbH)，1999年成立，总部位于德国不伦瑞克，是一家后基因组生物技术公司。ReliaTech主要专注于受体和配体的发现与研究。此外，ReliaTech也开发应用于血管与淋巴管生成研究的相关高品质试剂。目前ReliaTech提供近2800款产品，产品线主要包括重组蛋白(细胞因子、生长因子、可溶性受体)、抗体、ELISA试剂盒等。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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