ADAM-19 (a disintegrin and metalloprotease 19; also MADDAM and Meltrinβ) is a 95-100 kDa member of the M12B peptidase family of enzymes. It is expressed on multiple cell types including monocytes, fibroblasts, osteoblasts and dendritic cells. After cleavage of a signal sequence and prodomain, the ectodomain circulates in plasma bound to α2 Macroglobulin. ADAM19 cleaves at sequences present in myelin basic protein, insulin β chain, TNFα, TRANCE and SCF. Over amino acids (aa) 205-705, mouse ADAM19 shares 87% aa sequence identity with human ADAM19.
应用类型
WB
免疫原
该Anti-Mouse ADAM-19的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Mouse ADAM-19的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Mouse ADAM-19的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Mouse ADAM-19的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
