Kremen (Kringle-containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Two related members, Kremen-1 and -2, have been identified. Kremens bind a subset of the secreted Dickkopf (Dkk) proteins with high affinity. The canonical Wnt signaling pathway receptor complex composed of Wnt, the seven-transmembrane domain receptor Frizzled, and the receptor-related protein 5/6 (LRP5/6) coreceptor, is modulated by Kremens and Dkk proteins.
应用类型
WB
免疫原
该Anti-Mouse Kremen-1的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Mouse Kremen-1的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Mouse Kremen-1的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Mouse Kremen-1的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
