IGFBP5 is expressed by fibroblasts, myoblasts and osteoblasts, making it the predominant IGFBP found in bone extracts. IGFBP5 has a strong affinity for hydroxyapatite, allowing it to bind to bone cells. When bound to extracelluar matrix, IGFBP5 is protected from proteolysis and potentiates IGF activity, but when it is soluble, IGFBP5 is cleaved to a biologically inactive 21 kDa fragment. Mouse, human and rat IGFBP5 share 97% identity.
应用类型
WB
免疫原
该Anti-Mouse IGF-BP5的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Mouse IGF-BP5的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Mouse IGF-BP5的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Mouse IGF-BP5的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
